{"id":180,"date":"2023-02-17T22:37:13","date_gmt":"2023-02-17T22:37:13","guid":{"rendered":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/chapter\/3-1-apply-it\/"},"modified":"2023-08-21T02:03:59","modified_gmt":"2023-08-21T02:03:59","slug":"3-1-apply-it","status":"publish","type":"chapter","link":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/chapter\/3-1-apply-it\/","title":{"raw":"The Nervous System: Apply It","rendered":"The Nervous System: Apply It"},"content":{"raw":"<section class=\"textbox learningGoals\">\r\n<ul>\r\n \t<li>Describe the central nervous system<\/li>\r\n \t<li>Describe the structure and function of a neuron<\/li>\r\n \t<li>Describe how neurons communicate with each other<\/li>\r\n \t<li>Understand how neurotransmitters work and how drugs affect neurotransmitter systems<\/li>\r\n<\/ul>\r\n<\/section>In this section, you've learned about how the central nervous system works by using neurons to relay information throughout the body. Understanding how neurons communicate and how the brain works can provide insights for explaining behavior, but also in how to help those dealing with mental disorders.\r\n<h3>How Antidepressants Work<\/h3>\r\nDepression, which has been consistently linked with reduced serotonin levels, is commonly treated with selective serotonin reuptake inhibitors (SSRIs). While agonists and antagonists both operate by binding to receptor sites, reuptake inhibitors prevent unused neurotransmitters from being transported back to the neuron.\u00a0<span class=\"search-highlight first text last\" data-timestamp=\"1595958649302\" data-highlight-id=\"75af3672-7702-4845-8244-fd5fa0479217\" data-highlighted=\"true\">This allows neurotransmitters<\/span> to remain active in the synaptic cleft for longer durations, increasing their effectiveness. By preventing reuptake, SSRIs strengthen the effect of serotonin, giving it more time to interact with serotonin receptors on dendrites. Common SSRIs on the market today include Prozac, Paxil, and Zoloft. Some drugs can act as both antagonists <em>and<\/em> reuptake inhibitors, called SARIs (serotonin antagonist and reuptake inhibitors). SARIs are also primarily used to treat depression.\r\n\r\n<section class=\"textbox watchIt\">[embed]https:\/\/www.youtube.com\/watch?v=ClPVJ25Ka4k[\/embed]\r\n\r\nYou can view the\u00a0<a href=\"https:\/\/course-building.s3.us-west-2.amazonaws.com\/Intro+Psych\/How+do+antidepressants+work_+-+Neil+R.+Jeyasingam.txt\" target=\"_blank\" rel=\"noopener\">transcript for \u201cHow do antidepressants work? - Neil R. Jeyasingam\u201d here (opens in new window).<\/a><\/section><section class=\"textbox interact\"><iframe src=\"https:\/\/lumenlearning.h5p.com\/content\/1291874963780657438\/embed\" width=\"1088\" height=\"637\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\" aria-label=\"SSRIs\"><\/iframe><\/section><section><\/section>&nbsp;","rendered":"<section class=\"textbox learningGoals\">\n<ul>\n<li>Describe the central nervous system<\/li>\n<li>Describe the structure and function of a neuron<\/li>\n<li>Describe how neurons communicate with each other<\/li>\n<li>Understand how neurotransmitters work and how drugs affect neurotransmitter systems<\/li>\n<\/ul>\n<\/section>\n<p>In this section, you&#8217;ve learned about how the central nervous system works by using neurons to relay information throughout the body. Understanding how neurons communicate and how the brain works can provide insights for explaining behavior, but also in how to help those dealing with mental disorders.<\/p>\n<h3>How Antidepressants Work<\/h3>\n<p>Depression, which has been consistently linked with reduced serotonin levels, is commonly treated with selective serotonin reuptake inhibitors (SSRIs). While agonists and antagonists both operate by binding to receptor sites, reuptake inhibitors prevent unused neurotransmitters from being transported back to the neuron.\u00a0<span class=\"search-highlight first text last\" data-timestamp=\"1595958649302\" data-highlight-id=\"75af3672-7702-4845-8244-fd5fa0479217\" data-highlighted=\"true\">This allows neurotransmitters<\/span> to remain active in the synaptic cleft for longer durations, increasing their effectiveness. By preventing reuptake, SSRIs strengthen the effect of serotonin, giving it more time to interact with serotonin receptors on dendrites. Common SSRIs on the market today include Prozac, Paxil, and Zoloft. Some drugs can act as both antagonists <em>and<\/em> reuptake inhibitors, called SARIs (serotonin antagonist and reuptake inhibitors). SARIs are also primarily used to treat depression.<\/p>\n<section class=\"textbox watchIt\"><iframe loading=\"lazy\" id=\"oembed-1\" title=\"How do antidepressants work? - Neil R. Jeyasingam\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/ClPVJ25Ka4k?feature=oembed&#38;rel=0\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<p>You can view the\u00a0<a href=\"https:\/\/course-building.s3.us-west-2.amazonaws.com\/Intro+Psych\/How+do+antidepressants+work_+-+Neil+R.+Jeyasingam.txt\" target=\"_blank\" rel=\"noopener\">transcript for \u201cHow do antidepressants work? &#8211; Neil R. Jeyasingam\u201d here (opens in new window).<\/a><\/section>\n<section class=\"textbox interact\"><iframe loading=\"lazy\" src=\"https:\/\/lumenlearning.h5p.com\/content\/1291874963780657438\/embed\" width=\"1088\" height=\"637\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\" aria-label=\"SSRIs\"><\/iframe><\/section>\n<section><\/section>\n<p>&nbsp;<\/p>\n","protected":false},"author":20,"menu_order":8,"template":"","meta":{"_candela_citation":"[{\"type\":\"cc\",\"description\":\"Cells of the nervous system\",\"author\":\"\",\"organization\":\"OpenStax\",\"url\":\"https:\/\/openstax.org\/books\/psychology-2e\/pages\/3-2-cells-of-the-nervous-system\",\"project\":\"\",\"license\":\"cc-by\",\"license_terms\":\"Access for free at https:\/\/openstax.org\/books\/psychology-2e\/pages\/1-introduction\"},{\"type\":\"copyrighted_video\",\"description\":\"How do antidepressants work\",\"author\":\"\",\"organization\":\"TedEd\",\"url\":\"https:\/\/www.youtube.com\/watch?v=ClPVJ25Ka4k\",\"project\":\"\",\"license\":\"other\",\"license_terms\":\"Standard YouTube License\"}]","pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":[],"pb_section_license":""},"chapter-type":[],"contributor":[],"license":[],"part":210,"module-header":"apply_it","content_attributions":[{"type":"cc","description":"Cells of the nervous system","author":"","organization":"OpenStax","url":"https:\/\/openstax.org\/books\/psychology-2e\/pages\/3-2-cells-of-the-nervous-system","project":"","license":"cc-by","license_terms":"Access for free at https:\/\/openstax.org\/books\/psychology-2e\/pages\/1-introduction"},{"type":"copyrighted_video","description":"How do antidepressants work","author":"","organization":"TedEd","url":"https:\/\/www.youtube.com\/watch?v=ClPVJ25Ka4k","project":"","license":"other","license_terms":"Standard YouTube License"}],"internal_book_links":[],"video_content":null,"cc_video_embed_content":{"cc_scripts":"","media_targets":[]},"try_it_collection":null,"_links":{"self":[{"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/pressbooks\/v2\/chapters\/180"}],"collection":[{"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/wp\/v2\/users\/20"}],"version-history":[{"count":13,"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/pressbooks\/v2\/chapters\/180\/revisions"}],"predecessor-version":[{"id":5967,"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/pressbooks\/v2\/chapters\/180\/revisions\/5967"}],"part":[{"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/pressbooks\/v2\/parts\/210"}],"metadata":[{"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/pressbooks\/v2\/chapters\/180\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/wp\/v2\/media?parent=180"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/pressbooks\/v2\/chapter-type?post=180"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/wp\/v2\/contributor?post=180"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/wp\/v2\/license?post=180"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}