{"id":1282,"date":"2023-03-31T17:38:23","date_gmt":"2023-03-31T17:38:23","guid":{"rendered":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/chapter\/15-4-apply-it\/"},"modified":"2023-09-23T04:03:52","modified_gmt":"2023-09-23T04:03:52","slug":"15-4-apply-it","status":"publish","type":"chapter","link":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/chapter\/15-4-apply-it\/","title":{"raw":"Reconsolidation Therapy: Apply It","rendered":"Reconsolidation Therapy: Apply It"},"content":{"raw":"<section class=\"textbox learningGoals\">\r\n<ul>\r\n \t<li>Explain memory consolidation and how it can be manipulated using concepts from conditioning<\/li>\r\n \t<li>Describe how reconsolidation can be used to treat anxiety or PTSD<\/li>\r\n<\/ul>\r\n<\/section><a href=\"https:\/\/www.youtube.com\/watch?v=pM3G6kITdYk&amp;list=PLGunxoYymtFgFthRcyjfXluJH7rbXXyGk&amp;index=2&amp;t=0s\" target=\"_blank\" rel=\"noopener\">This video explains some of the remarkable work of Merel Kindt<\/a>, a therapist and memory researcher. Dr. Kindt uses the drug propranolol, which interferes with the reconsolidation of the fear aspect of a memory, though it does not prevent the person from feeling fear during the training session nor does it interfere with the person\u2019s memory for the events that occurred. In the video, she works with a person terrified of cats and another who fears spiders.\r\n\r\n<section class=\"textbox watchIt\"><iframe title=\"YouTube video player\" src=\"https:\/\/www.youtube.com\/embed\/pM3G6kITdYk?start=118\" width=\"560\" height=\"315\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe>\r\nYou can view the\u00a0<a href=\"https:\/\/course-building.s3.us-west-2.amazonaws.com\/Intro+Psych\/A+Little+Closer+_+A+Cure+For+Fear_+Part+1+_+Topic.txt\" target=\"_blank\" rel=\"noopener\">transcript for \u201cA Little Closer | A Cure For Fear: Part 1 | Topic\u201d here (opens in new window).<\/a><\/section><section class=\"textbox tryIt\">[ohm2_question height=\"800\"]11112[\/ohm2_question]<\/section>As you can see from the video, therapists can now use the new insights coming from research on memory reconsolidation to help in their treatment of people with disorders that include memory dysfunctions.\r\n\r\nA 2010 study published in the journal <em>Nature<\/em> showed that reconsolidation therapy was effective in reducing anxiety responses in people with phobias. In the study, participants were exposed to a fear-inducing stimulus (in this case, a spider) while taking beta-blockers, which interfere with the memory retrieval process. Compared with participants who received a placebo, those who received the beta-blockers showed a significantly reduced fear response when re-exposed to the spider a few days later.[footnote]Schiller, D., Monfils, M. H., Raio, C. M., Johnson, D. C., Ledoux, J. E., &amp; Phelps, E. A. (2010). Preventing the return of fear in humans using reconsolidation update mechanisms. <em>Nature<\/em>, 463(7277), 49-53. https:\/\/doi.org\/10.1038\/nature08637[\/footnote]\r\n\r\nAnother study, published in 2017 in the journal Psychotherapy and Psychosomatics, looked at the use of reconsolidation therapy in the treatment of anxiety related to public speaking, but found that those who received propranolol did not differ significantly from the placebo group.[footnote]Elsey, J. W. B., Filmer, A. I., Galvin, H. R., Kurath, J. D., Vossoughi, L., Thomander, L. S., Zavodnik, M., &amp; Kindt, M. (2020). Reconsolidation-based treatment for fear of public speaking: a systematic pilot study using propranolol. <i>Translational psychiatry<\/i>,\u00a0<i>10<\/i>(1), 179. https:\/\/doi.org\/10.1038\/s41398-020-0857-z[\/footnote]\r\n\r\nA 2021 study revealed that memory reconsolidation can be an effective treatment for PTSD, though more research is needed to verify the reliability of the research.[footnote]Astill Wright, L., Horstmann, L., Holmes, E. A., &amp; Bisson, J. I. (2021). Consolidation\/reconsolidation therapies for the prevention and treatment of PTSD and re-experiencing: A systematic review and meta-analysis. T<em>ranslational Psychiatry<\/em>, 11(1), 1-14. https:\/\/doi.org\/10.1038\/s41398-021-01570-w[\/footnote]","rendered":"<section class=\"textbox learningGoals\">\n<ul>\n<li>Explain memory consolidation and how it can be manipulated using concepts from conditioning<\/li>\n<li>Describe how reconsolidation can be used to treat anxiety or PTSD<\/li>\n<\/ul>\n<\/section>\n<p><a href=\"https:\/\/www.youtube.com\/watch?v=pM3G6kITdYk&amp;list=PLGunxoYymtFgFthRcyjfXluJH7rbXXyGk&amp;index=2&amp;t=0s\" target=\"_blank\" rel=\"noopener\">This video explains some of the remarkable work of Merel Kindt<\/a>, a therapist and memory researcher. Dr. Kindt uses the drug propranolol, which interferes with the reconsolidation of the fear aspect of a memory, though it does not prevent the person from feeling fear during the training session nor does it interfere with the person\u2019s memory for the events that occurred. In the video, she works with a person terrified of cats and another who fears spiders.<\/p>\n<section class=\"textbox watchIt\"><iframe loading=\"lazy\" title=\"YouTube video player\" src=\"https:\/\/www.youtube.com\/embed\/pM3G6kITdYk?start=118\" width=\"560\" height=\"315\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><br \/>\nYou can view the\u00a0<a href=\"https:\/\/course-building.s3.us-west-2.amazonaws.com\/Intro+Psych\/A+Little+Closer+_+A+Cure+For+Fear_+Part+1+_+Topic.txt\" target=\"_blank\" rel=\"noopener\">transcript for \u201cA Little Closer | A Cure For Fear: Part 1 | Topic\u201d here (opens in new window).<\/a><\/section>\n<section class=\"textbox tryIt\"><iframe loading=\"lazy\" id=\"ohm11112\" class=\"resizable\" src=\"https:\/\/ohm.one.lumenlearning.com\/multiembedq.php?id=11112&theme=lumen&iframe_resize_id=ohm11112&source=tnh&show_question_numbers\" width=\"100%\" height=\"800\"><\/iframe><\/section>\n<p>As you can see from the video, therapists can now use the new insights coming from research on memory reconsolidation to help in their treatment of people with disorders that include memory dysfunctions.<\/p>\n<p>A 2010 study published in the journal <em>Nature<\/em> showed that reconsolidation therapy was effective in reducing anxiety responses in people with phobias. In the study, participants were exposed to a fear-inducing stimulus (in this case, a spider) while taking beta-blockers, which interfere with the memory retrieval process. Compared with participants who received a placebo, those who received the beta-blockers showed a significantly reduced fear response when re-exposed to the spider a few days later.<a class=\"footnote\" title=\"Schiller, D., Monfils, M. H., Raio, C. M., Johnson, D. C., Ledoux, J. E., &amp; Phelps, E. A. (2010). Preventing the return of fear in humans using reconsolidation update mechanisms. Nature, 463(7277), 49-53. https:\/\/doi.org\/10.1038\/nature08637\" id=\"return-footnote-1282-1\" href=\"#footnote-1282-1\" aria-label=\"Footnote 1\"><sup class=\"footnote\">[1]<\/sup><\/a><\/p>\n<p>Another study, published in 2017 in the journal Psychotherapy and Psychosomatics, looked at the use of reconsolidation therapy in the treatment of anxiety related to public speaking, but found that those who received propranolol did not differ significantly from the placebo group.<a class=\"footnote\" title=\"Elsey, J. W. B., Filmer, A. I., Galvin, H. R., Kurath, J. D., Vossoughi, L., Thomander, L. S., Zavodnik, M., &amp; Kindt, M. (2020). Reconsolidation-based treatment for fear of public speaking: a systematic pilot study using propranolol. Translational psychiatry,\u00a010(1), 179. https:\/\/doi.org\/10.1038\/s41398-020-0857-z\" id=\"return-footnote-1282-2\" href=\"#footnote-1282-2\" aria-label=\"Footnote 2\"><sup class=\"footnote\">[2]<\/sup><\/a><\/p>\n<p>A 2021 study revealed that memory reconsolidation can be an effective treatment for PTSD, though more research is needed to verify the reliability of the research.<a class=\"footnote\" title=\"Astill Wright, L., Horstmann, L., Holmes, E. A., &amp; Bisson, J. I. (2021). Consolidation\/reconsolidation therapies for the prevention and treatment of PTSD and re-experiencing: A systematic review and meta-analysis. Translational Psychiatry, 11(1), 1-14. https:\/\/doi.org\/10.1038\/s41398-021-01570-w\" id=\"return-footnote-1282-3\" href=\"#footnote-1282-3\" aria-label=\"Footnote 3\"><sup class=\"footnote\">[3]<\/sup><\/a><\/p>\n<hr class=\"before-footnotes clear\" \/><div class=\"footnotes\"><ol><li id=\"footnote-1282-1\">Schiller, D., Monfils, M. H., Raio, C. M., Johnson, D. C., Ledoux, J. E., &amp; Phelps, E. A. (2010). Preventing the return of fear in humans using reconsolidation update mechanisms. <em>Nature<\/em>, 463(7277), 49-53. https:\/\/doi.org\/10.1038\/nature08637 <a href=\"#return-footnote-1282-1\" class=\"return-footnote\" aria-label=\"Return to footnote 1\">&crarr;<\/a><\/li><li id=\"footnote-1282-2\">Elsey, J. W. B., Filmer, A. I., Galvin, H. R., Kurath, J. D., Vossoughi, L., Thomander, L. S., Zavodnik, M., &amp; Kindt, M. (2020). Reconsolidation-based treatment for fear of public speaking: a systematic pilot study using propranolol. <i>Translational psychiatry<\/i>,\u00a0<i>10<\/i>(1), 179. https:\/\/doi.org\/10.1038\/s41398-020-0857-z <a href=\"#return-footnote-1282-2\" class=\"return-footnote\" aria-label=\"Return to footnote 2\">&crarr;<\/a><\/li><li id=\"footnote-1282-3\">Astill Wright, L., Horstmann, L., Holmes, E. A., &amp; Bisson, J. I. (2021). Consolidation\/reconsolidation therapies for the prevention and treatment of PTSD and re-experiencing: A systematic review and meta-analysis. T<em>ranslational Psychiatry<\/em>, 11(1), 1-14. https:\/\/doi.org\/10.1038\/s41398-021-01570-w <a href=\"#return-footnote-1282-3\" class=\"return-footnote\" aria-label=\"Return to footnote 3\">&crarr;<\/a><\/li><\/ol><\/div>","protected":false},"author":20,"menu_order":23,"template":"","meta":{"_candela_citation":"[{\"type\":\"cc\",\"description\":\"Psychology in Real Life: Reconsolidation\",\"author\":\"Patrick Carroll for Lumen Learning\",\"organization\":\"Lumen Learning\",\"url\":\"\",\"project\":\"\",\"license\":\"cc-by\",\"license_terms\":\"\"},{\"type\":\"copyrighted_video\",\"description\":\"Psychology- Merel Kindt\\'s Studies\",\"author\":\"Tom Staveley\",\"organization\":\"Psychology- Merel Kindt\\'s Studies\",\"url\":\"https:\/\/www.youtube.com\/watch?v=HDXWBHCusqs\",\"project\":\"\",\"license\":\"other\",\"license_terms\":\"Standard YouTube License\"},{\"type\":\"copyrighted_video\",\"description\":\"A Little Closer | A Cure For Fear: Part 1 \",\"author\":\"\",\"organization\":\"Topic\",\"url\":\"https:\/\/youtu.be\/pM3G6kITdYk?list=PLGunxoYymtFgFthRcyjfXluJH7rbXXyGk\",\"project\":\"\",\"license\":\"other\",\"license_terms\":\"Standard YouTube License\"}]","pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":[],"pb_section_license":""},"chapter-type":[],"contributor":[],"license":[],"part":1260,"module-header":"apply_it","content_attributions":null,"internal_book_links":[],"video_content":null,"cc_video_embed_content":{"cc_scripts":"","media_targets":[]},"try_it_collection":null,"_links":{"self":[{"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/pressbooks\/v2\/chapters\/1282"}],"collection":[{"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/wp\/v2\/users\/20"}],"version-history":[{"count":12,"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/pressbooks\/v2\/chapters\/1282\/revisions"}],"predecessor-version":[{"id":6222,"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/pressbooks\/v2\/chapters\/1282\/revisions\/6222"}],"part":[{"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/pressbooks\/v2\/parts\/1260"}],"metadata":[{"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/pressbooks\/v2\/chapters\/1282\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/wp\/v2\/media?parent=1282"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/pressbooks\/v2\/chapter-type?post=1282"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/wp\/v2\/contributor?post=1282"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/wp-json\/wp\/v2\/license?post=1282"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}