{"id":1271,"date":"2023-03-31T17:38:16","date_gmt":"2023-03-31T17:38:16","guid":{"rendered":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/chapter\/biomedical-therapies\/"},"modified":"2026-01-21T15:47:20","modified_gmt":"2026-01-21T15:47:20","slug":"biomedical-therapies","status":"publish","type":"chapter","link":"https:\/\/content.one.lumenlearning.com\/introductiontopsychology\/chapter\/biomedical-therapies\/","title":{"raw":"Humanistic and Biomedical Therapies: Learn It 2\u2014Biomedical Therapies","rendered":"Humanistic and Biomedical Therapies: Learn It 2\u2014Biomedical Therapies"},"content":{"raw":"<h2>Biomedical Therapies<\/h2>\r\n<p class=\"p1\">Beginning in the mid-20th century, new medical treatments (especially medications) transformed mental health care. Today, <span class=\"s1\"><b>biomedical therapies<\/b><\/span> are used to reduce symptoms by targeting brain and body processes involved in mood, thinking, attention, sleep, and arousal. Many people use biomedical therapies <span class=\"s1\"><b>alongside psychotherapy<\/b><\/span>, while others use them on their own\u2014especially when symptoms are severe or urgent.<\/p>\r\n<section class=\"textbox keyTakeaway\">\r\n<h3>biomedical therapy<\/h3>\r\n<p class=\"p1\"><span class=\"s1\"><b>Biomedical therapies<\/b><\/span> are treatments for psychological disorders that use medical approaches\u2014most commonly <span class=\"s1\"><b>prescription medications<\/b><\/span> and <span class=\"s1\"><b>brain-stimulation therapies<\/b><\/span> (such as ECT or TMS). These approaches are often used when symptoms significantly impair daily functioning, when safety is a concern, or when psychotherapy alone is not enough.<\/p>\r\n<\/section>\r\n<h2>Psychotropic Medications<\/h2>\r\n<p class=\"p1\"><span class=\"s1\"><b>Psychotropic medications<\/b><\/span> are prescription drugs that affect brain chemistry and are used to treat symptoms of psychological disorders. They are prescribed by medical clinicians (including psychiatrists and other physicians, and in some settings nurse practitioners or physician assistants). The field focused on medication treatment for mental health is often called <span class=\"s1\"><b>psychopharmacology<\/b><\/span>.<\/p>\r\n<p class=\"p1\">Medications usually <span class=\"s1\"><b>manage symptoms rather than \u201ccure\u201d<\/b><\/span> a disorder. Some are used short-term; others are used long-term to reduce relapse risk and improve daily functioning. Medication decisions typically involve trial-and-adjustment, ongoing monitoring, and shared decision-making around benefits, side effects, and goals.<\/p>\r\n<table>\r\n<thead>\r\n<tr>\r\n<th colspan=\"5\">\r\n<p class=\"p1\"><span style=\"font-family: inherit; font-size: inherit; font-weight: 400;\">Table 1. Commonly Prescribed Psychotropic Medications<\/span><\/p>\r\n<\/th>\r\n<\/tr>\r\n<tr>\r\n<th>\r\n<p class=\"p1\"><b>Medication class<\/b><\/p>\r\n<\/th>\r\n<th>\r\n<p class=\"p1\"><b>Often used for<\/b><\/p>\r\n<\/th>\r\n<th>\r\n<p class=\"p1\"><b>Examples (brand\/generic)<\/b><\/p>\r\n<\/th>\r\n<th>\r\n<p class=\"p1\"><b>General mechanism (simplified)<\/b><\/p>\r\n<\/th>\r\n<th>\r\n<p class=\"p1\"><b>Key considerations \/ common risks<\/b><\/p>\r\n<\/th>\r\n<\/tr>\r\n<\/thead>\r\n<tbody>\r\n<tr>\r\n<td>\r\n<p class=\"p1\"><span class=\"s1\"><b>Antipsychotics<\/b><\/span> (first-generation)<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">Psychosis (e.g., schizophrenia), acute mania<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">haloperidol (Haldol)<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">primarily reduces dopamine signaling<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">higher risk of movement-related side effects, including <span class=\"s1\"><b>tardive dyskinesia<\/b><\/span><\/p>\r\n<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\r\n<p class=\"p1\"><span class=\"s1\"><b>Antipsychotics<\/b><\/span> (second-generation\/\u201catypical\u201d)<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">Psychosis; sometimes bipolar disorder; sometimes adjunct for depression<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">risperidone (Risperdal), aripiprazole (Abilify), olanzapine (Zyprexa), clozapine (Clozaril)<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">dopamine + serotonin pathways<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">higher risk of <span class=\"s1\"><b>weight gain\/metabolic effects<\/b><\/span> (varies by medication); clozapine requires careful blood monitoring<\/p>\r\n<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\r\n<p class=\"p1\"><span class=\"s1\"><b>Antidepressants<\/b><\/span> (SSRIs\/SNRIs and others)<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">Depression; many anxiety disorders<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">sertraline (Zoloft), fluoxetine (Prozac), escitalopram (Lexapro); venlafaxine (Effexor)<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">increases availability of serotonin and\/or norepinephrine<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">side effects can include GI upset, sleep changes, sexual side effects; tapering may be needed to avoid withdrawal-like symptoms<\/p>\r\n<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\r\n<p class=\"p1\"><b>Anti-anxiety medications<\/b><span class=\"s1\"> (benzodiazepines)<\/span><\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">Short-term acute anxiety\/panic; agitation; insomnia (select cases)<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">lorazepam (Ativan), alprazolam (Xanax)<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">increases GABA activity (calming effect)<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">can cause sedation; <span class=\"s1\"><b>dependence risk<\/b><\/span> increases with longer use<\/p>\r\n<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\r\n<p class=\"p1\"><span class=\"s1\"><b>Anxiolytic<\/b><\/span> (non-benzodiazepine)<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">Generalized anxiety (select cases)<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">buspirone (Buspar)<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">affects serotonin receptors<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">slower onset than benzodiazepines; typically not habit-forming<\/p>\r\n<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\r\n<p class=\"p1\"><b>Mood stabilizers<\/b><\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">Bipolar disorder (mania prevention; sometimes depression prevention)<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">lithium; valproate (Depakote); lamotrigine (Lamictal)<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">varies by medication<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">requires monitoring (e.g., lithium levels); side effects vary widely by medication<\/p>\r\n<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\r\n<p class=\"p1\"><b>Stimulants<\/b><\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">ADHD<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">methylphenidate (Ritalin), amphetamine salts (Adderall)<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">increases dopamine\/norepinephrine activity<\/p>\r\n<\/td>\r\n<td>\r\n<p class=\"p1\">can reduce appetite and disrupt sleep; monitoring is important<\/p>\r\n<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<h2><b>Brain-Stimulation and Rapid-Acting Biomedical Treatments<\/b><\/h2>\r\n<p class=\"p3\">Some biomedical therapies use electricity, magnetic fields, implanted devices, or rapid-acting medications to change brain activity patterns.<\/p>\r\n<section class=\"textbox keyTakeaway\">\r\n<h3>electroconvulsive therapy (ECT)<\/h3>\r\n<p><strong>Electroconvulsive therapy (ECT), <\/strong>uses a carefully controlled electrical stimulus to produce a brief seizure. Modern ECT is done <span class=\"s1\"><b>with anesthesia and medical monitoring<\/b><\/span>. It is most commonly used for <span class=\"s1\"><b>severe depression<\/b><\/span>, especially when symptoms are urgent or when other treatments have not helped. A major concern is <span class=\"s1\"><b>memory side effects<\/b><\/span>, especially around the time of treatment.<\/p>\r\n<\/section>\r\n<p>An alternative to ECT is <strong>transcranial magnetic stimulation (TMS)<\/strong>, a procedure approved by the FDA in 2008 that uses magnetic fields to stimulate nerve cells in the brain to improve depression symptoms. It does <span class=\"s1\">not<\/span> require anesthesia and does <span class=\"s1\">not<\/span> induce a seizure. It is used when other treatments have not worked (Mayo Clinic, 2012).<\/p>\r\n<h3><b>Deep brain stimulation (DBS)<\/b><\/h3>\r\n<p class=\"p3\"><span class=\"s2\"><b>DBS<\/b><\/span> involves surgically implanted electrodes that deliver stimulation to specific brain circuits. In mental health, DBS has been used in very limited cases (typically severe, treatment-resistant conditions). The FDA has granted a <span class=\"s2\">Humanitarian Device Exemption (HDE)<\/span> for a DBS system for <span class=\"s2\">refractory obsessive-compulsive disorder<\/span> in adults (a narrow, specialized indication).<span class=\"Apple-converted-space\">\u00a0 <\/span><\/p>\r\n<h3><b>Vagus nerve stimulation (VNS)<\/b><\/h3>\r\n<p class=\"p3\"><span class=\"s2\"><b>VNS<\/b><\/span> uses an implanted device to send stimulation through the vagus nerve. The treatment involves sending regular, mild pulses of electrical energy to the brain via the vagus nerve, a large nerve in the neck. This is achieved through a device that is surgically implanted under the skin in the chest, similar to a pacemaker. A wire (lead) connected to this device is wound around the vagus nerve in the neck. The electrical pulses are delivered to the nerve by the device periodically throughout the day. It has long been used for epilepsy and has also received FDA approval for <span class=\"s2\"><b>treatment-resistant depression<\/b><\/span> under specific conditions and monitoring requirements.<span class=\"Apple-converted-space\">\u00a0 <\/span><\/p>\r\n<h3><b>Ketamine-assisted therapy and intranasal esketamine<\/b><\/h3>\r\n<p><b>Ketamine-assisted therapy <\/b>is<b><\/b> rapid-acting treatment for people with treatment-resistant depression (and other conditions like PTSD, chronic pain, or substance-abused disorders). Low-dose ketamine, a type of anesthetic (often given as six IV infusions over 2\u20134 weeks, or as intranasal esketamine) works by boosting glutamate-driven synapse growth. Relief can appear within hours and is paired with follow-up therapy sessions to reinforce lasting change. Clinics screen for cardiovascular and psychosis risk, monitor patients for about two hours post-dose, and reserve ketamine for those who haven\u2019t improved on standard medications.<\/p>\r\n<section class=\"textbox connectIt\">A buzzword in therapy today is<strong> evidence-based practice<\/strong>. However, it\u2019s not a novel concept but one that has been used in medicine for at least two decades. Evidence-based practice is used to reduce errors in treatment selection by making clinical decisions based on research (Sackett &amp; Rosenberg, 1995). In any case, evidence-based treatment is on the rise in the field of psychology. So what is it, and why does it matter?\r\n\r\n<p>In an effort to determine which treatment methodologies are evidenced-based, professional organizations such as the American Psychological Association (APA) have recommended that specific psychological treatments be used to treat certain psychological disorders (Chambless &amp; Ollendick, 2001). According to the APA (2005), \u201cEvidence-based practice in psychology (EBPP) is the integration of the best available research with clinical expertise in the context of patient characteristics, culture, and preferences\u201d (p. 1).<\/p>\r\n<p>The foundational idea behind evidence-based treatment is that best practices are determined by research evidence that has been compiled by comparing various forms of treatment (Charman &amp; Barkham, 2005). These treatments are then operationalized and placed in treatment manuals\u2014trained therapists follow these manuals. The benefits are that evidence-based treatment can reduce variability between therapists to ensure that a specific approach is delivered with integrity (Charman &amp; Barkham, 2005). Therefore, clients have a higher chance of receiving therapeutic interventions that are effective at treating their specific disorder. While EBPP is based on randomized control trials, critics of EBPP reject it stating that the results of trials cannot be applied to individuals and instead determinations regarding treatment should be based on a therapist\u2019s judgment (Mullen &amp; Streiner, 2004).<\/p>\r\n<\/section>\r\n<section class=\"textbox tryIt\">\r\n<div class=\"group w-full text-token-text-primary border-b border-black\/10 gizmo:border-0 dark:border-gray-900\/50 gizmo:dark:border-0 gizmo:bg-transparent dark:bg-gray-800 gizmo:dark:bg-transparent\" data-testid=\"conversation-turn-66\">\r\n<div class=\"p-4 justify-center text-base md:gap-6 md:py-6 m-auto\">\r\n<div class=\"flex flex-1 gap-4 text-base mx-auto md:gap-6 gizmo:gap-3 gizmo:md:px-5 gizmo:lg:px-1 gizmo:xl:px-5 md:max-w-2xl lg:max-w-[38rem] gizmo:md:max-w-3xl gizmo:lg:max-w-[40rem] gizmo:xl:max-w-[48rem] xl:max-w-3xl }\">\r\n<div class=\"relative flex w-[calc(100%-50px)] flex-col gap-1 gizmo:w-full md:gap-3 lg:w-[calc(100%-115px)] gizmo:text-gizmo-gray-600 gizmo:dark:text-gray-300\">\r\n<div class=\"flex flex-grow flex-col gap-3 max-w-full\">\r\n<div class=\"min-h-[20px] flex flex-col items-start gap-3 overflow-x-auto whitespace-pre-wrap break-words\">\r\n<div class=\"\">What are some of the advantages and limitations of using biomedical therapies like psychotropic medications and electroconvulsive therapy (ECT) in the treatment of psychological disorders?<\/div>\r\n<\/div>\r\n<\/div>\r\n<div class=\"text-gray-400 flex self-end lg:self-center justify-center gizmo:lg:justify-start mt-2 gizmo:mt-0 invisible lg:gap-1 lg:absolute lg:top-0 lg:translate-x-full lg:right-0 lg:mt-0 lg:pl-2 gap-2 md:gap-3 gizmo:absolute gizmo:right-0 gizmo:top-1\/2 gizmo:-translate-y-1\/2 gizmo:transform\"><br \/>\r\n[reveal-answer q=\"636269\"]Show Answer[\/reveal-answer]<br \/>\r\n[hidden-answer a=\"636269\"]\r\n\r\n<h3>Advantages of Biomedical Therapies<\/h3>\r\n<ol>\r\n\t<li>\r\n<p><strong>Immediate Relief<\/strong>: Psychotropic medications often provide quick relief from acute symptoms, making it easier for patients to participate in psychotherapy.<\/p>\r\n<\/li>\r\n\t<li>\r\n<p><strong>Accessibility<\/strong>: Medications are widely available and can be administered by general physicians, making treatment more accessible for many people.<\/p>\r\n<\/li>\r\n\t<li>\r\n<p><strong>Scientifically Backed<\/strong>: Treatments like ECT have shown high efficacy rates in treating severe depression and are often considered when other treatments fail.<\/p>\r\n<\/li>\r\n\t<li>\r\n<p><strong>Broad Application<\/strong>: Biomedical therapies can treat a wide range of psychological disorders, from depression and anxiety to schizophrenia and bipolar disorder.<\/p>\r\n<\/li>\r\n<\/ol>\r\n<h3>Limitations of Biomedical Therapies<\/h3>\r\n<ol>\r\n\t<li>\r\n<p><strong>Side Effects<\/strong>: Psychotropic medications often come with a range of side effects, from mild (e.g., drowsiness, nausea) to severe (e.g., tardive dyskinesia, increased risk of suicide).<\/p>\r\n<\/li>\r\n\t<li>\r\n<p><strong>Symptom Treatment, Not Cure<\/strong>: These therapies generally treat the symptoms but do not cure the underlying psychological disorder.<\/p>\r\n<\/li>\r\n\t<li>\r\n<p><strong>Over-reliance<\/strong>: There's a risk of becoming overly reliant on medication, which can sometimes deter patients from pursuing other forms of treatment like psychotherapy.<\/p>\r\n<\/li>\r\n\t<li>\r\n<p><strong>Stigma<\/strong>: Both medication and especially ECT carry a societal stigma, which can affect a patient's willingness to seek treatment.<\/p>\r\n<\/li>\r\n\t<li>\r\n<p><strong>Cost<\/strong>: Some of these treatments, particularly newer medications and procedures like deep brain stimulation, can be expensive and may not be covered by insurance.<\/p>\r\n<\/li>\r\n\t<li>\r\n<p><strong>Ethical Concerns<\/strong>: In the case of ECT, there are ethical considerations given its invasive nature and the potential for memory loss.<\/p>\r\n<\/li>\r\n<\/ol>\r\n\r\n[\/hidden-answer]<\/div>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<\/section>\r\n<p>&nbsp;<\/p>","rendered":"<h2>Biomedical Therapies<\/h2>\n<p class=\"p1\">Beginning in the mid-20th century, new medical treatments (especially medications) transformed mental health care. Today, <span class=\"s1\"><b>biomedical therapies<\/b><\/span> are used to reduce symptoms by targeting brain and body processes involved in mood, thinking, attention, sleep, and arousal. Many people use biomedical therapies <span class=\"s1\"><b>alongside psychotherapy<\/b><\/span>, while others use them on their own\u2014especially when symptoms are severe or urgent.<\/p>\n<section class=\"textbox keyTakeaway\">\n<h3>biomedical therapy<\/h3>\n<p class=\"p1\"><span class=\"s1\"><b>Biomedical therapies<\/b><\/span> are treatments for psychological disorders that use medical approaches\u2014most commonly <span class=\"s1\"><b>prescription medications<\/b><\/span> and <span class=\"s1\"><b>brain-stimulation therapies<\/b><\/span> (such as ECT or TMS). These approaches are often used when symptoms significantly impair daily functioning, when safety is a concern, or when psychotherapy alone is not enough.<\/p>\n<\/section>\n<h2>Psychotropic Medications<\/h2>\n<p class=\"p1\"><span class=\"s1\"><b>Psychotropic medications<\/b><\/span> are prescription drugs that affect brain chemistry and are used to treat symptoms of psychological disorders. They are prescribed by medical clinicians (including psychiatrists and other physicians, and in some settings nurse practitioners or physician assistants). The field focused on medication treatment for mental health is often called <span class=\"s1\"><b>psychopharmacology<\/b><\/span>.<\/p>\n<p class=\"p1\">Medications usually <span class=\"s1\"><b>manage symptoms rather than \u201ccure\u201d<\/b><\/span> a disorder. Some are used short-term; others are used long-term to reduce relapse risk and improve daily functioning. Medication decisions typically involve trial-and-adjustment, ongoing monitoring, and shared decision-making around benefits, side effects, and goals.<\/p>\n<table>\n<thead>\n<tr>\n<th colspan=\"5\">\n<p class=\"p1\"><span style=\"font-family: inherit; font-size: inherit; font-weight: 400;\">Table 1. Commonly Prescribed Psychotropic Medications<\/span><\/p>\n<\/th>\n<\/tr>\n<tr>\n<th>\n<p class=\"p1\"><b>Medication class<\/b><\/p>\n<\/th>\n<th>\n<p class=\"p1\"><b>Often used for<\/b><\/p>\n<\/th>\n<th>\n<p class=\"p1\"><b>Examples (brand\/generic)<\/b><\/p>\n<\/th>\n<th>\n<p class=\"p1\"><b>General mechanism (simplified)<\/b><\/p>\n<\/th>\n<th>\n<p class=\"p1\"><b>Key considerations \/ common risks<\/b><\/p>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\n<p class=\"p1\"><span class=\"s1\"><b>Antipsychotics<\/b><\/span> (first-generation)<\/p>\n<\/td>\n<td>\n<p class=\"p1\">Psychosis (e.g., schizophrenia), acute mania<\/p>\n<\/td>\n<td>\n<p class=\"p1\">haloperidol (Haldol)<\/p>\n<\/td>\n<td>\n<p class=\"p1\">primarily reduces dopamine signaling<\/p>\n<\/td>\n<td>\n<p class=\"p1\">higher risk of movement-related side effects, including <span class=\"s1\"><b>tardive dyskinesia<\/b><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<p class=\"p1\"><span class=\"s1\"><b>Antipsychotics<\/b><\/span> (second-generation\/\u201catypical\u201d)<\/p>\n<\/td>\n<td>\n<p class=\"p1\">Psychosis; sometimes bipolar disorder; sometimes adjunct for depression<\/p>\n<\/td>\n<td>\n<p class=\"p1\">risperidone (Risperdal), aripiprazole (Abilify), olanzapine (Zyprexa), clozapine (Clozaril)<\/p>\n<\/td>\n<td>\n<p class=\"p1\">dopamine + serotonin pathways<\/p>\n<\/td>\n<td>\n<p class=\"p1\">higher risk of <span class=\"s1\"><b>weight gain\/metabolic effects<\/b><\/span> (varies by medication); clozapine requires careful blood monitoring<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<p class=\"p1\"><span class=\"s1\"><b>Antidepressants<\/b><\/span> (SSRIs\/SNRIs and others)<\/p>\n<\/td>\n<td>\n<p class=\"p1\">Depression; many anxiety disorders<\/p>\n<\/td>\n<td>\n<p class=\"p1\">sertraline (Zoloft), fluoxetine (Prozac), escitalopram (Lexapro); venlafaxine (Effexor)<\/p>\n<\/td>\n<td>\n<p class=\"p1\">increases availability of serotonin and\/or norepinephrine<\/p>\n<\/td>\n<td>\n<p class=\"p1\">side effects can include GI upset, sleep changes, sexual side effects; tapering may be needed to avoid withdrawal-like symptoms<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<p class=\"p1\"><b>Anti-anxiety medications<\/b><span class=\"s1\"> (benzodiazepines)<\/span><\/p>\n<\/td>\n<td>\n<p class=\"p1\">Short-term acute anxiety\/panic; agitation; insomnia (select cases)<\/p>\n<\/td>\n<td>\n<p class=\"p1\">lorazepam (Ativan), alprazolam (Xanax)<\/p>\n<\/td>\n<td>\n<p class=\"p1\">increases GABA activity (calming effect)<\/p>\n<\/td>\n<td>\n<p class=\"p1\">can cause sedation; <span class=\"s1\"><b>dependence risk<\/b><\/span> increases with longer use<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<p class=\"p1\"><span class=\"s1\"><b>Anxiolytic<\/b><\/span> (non-benzodiazepine)<\/p>\n<\/td>\n<td>\n<p class=\"p1\">Generalized anxiety (select cases)<\/p>\n<\/td>\n<td>\n<p class=\"p1\">buspirone (Buspar)<\/p>\n<\/td>\n<td>\n<p class=\"p1\">affects serotonin receptors<\/p>\n<\/td>\n<td>\n<p class=\"p1\">slower onset than benzodiazepines; typically not habit-forming<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<p class=\"p1\"><b>Mood stabilizers<\/b><\/p>\n<\/td>\n<td>\n<p class=\"p1\">Bipolar disorder (mania prevention; sometimes depression prevention)<\/p>\n<\/td>\n<td>\n<p class=\"p1\">lithium; valproate (Depakote); lamotrigine (Lamictal)<\/p>\n<\/td>\n<td>\n<p class=\"p1\">varies by medication<\/p>\n<\/td>\n<td>\n<p class=\"p1\">requires monitoring (e.g., lithium levels); side effects vary widely by medication<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<p class=\"p1\"><b>Stimulants<\/b><\/p>\n<\/td>\n<td>\n<p class=\"p1\">ADHD<\/p>\n<\/td>\n<td>\n<p class=\"p1\">methylphenidate (Ritalin), amphetamine salts (Adderall)<\/p>\n<\/td>\n<td>\n<p class=\"p1\">increases dopamine\/norepinephrine activity<\/p>\n<\/td>\n<td>\n<p class=\"p1\">can reduce appetite and disrupt sleep; monitoring is important<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2><b>Brain-Stimulation and Rapid-Acting Biomedical Treatments<\/b><\/h2>\n<p class=\"p3\">Some biomedical therapies use electricity, magnetic fields, implanted devices, or rapid-acting medications to change brain activity patterns.<\/p>\n<section class=\"textbox keyTakeaway\">\n<h3>electroconvulsive therapy (ECT)<\/h3>\n<p><strong>Electroconvulsive therapy (ECT), <\/strong>uses a carefully controlled electrical stimulus to produce a brief seizure. Modern ECT is done <span class=\"s1\"><b>with anesthesia and medical monitoring<\/b><\/span>. It is most commonly used for <span class=\"s1\"><b>severe depression<\/b><\/span>, especially when symptoms are urgent or when other treatments have not helped. A major concern is <span class=\"s1\"><b>memory side effects<\/b><\/span>, especially around the time of treatment.<\/p>\n<\/section>\n<p>An alternative to ECT is <strong>transcranial magnetic stimulation (TMS)<\/strong>, a procedure approved by the FDA in 2008 that uses magnetic fields to stimulate nerve cells in the brain to improve depression symptoms. It does <span class=\"s1\">not<\/span> require anesthesia and does <span class=\"s1\">not<\/span> induce a seizure. It is used when other treatments have not worked (Mayo Clinic, 2012).<\/p>\n<h3><b>Deep brain stimulation (DBS)<\/b><\/h3>\n<p class=\"p3\"><span class=\"s2\"><b>DBS<\/b><\/span> involves surgically implanted electrodes that deliver stimulation to specific brain circuits. In mental health, DBS has been used in very limited cases (typically severe, treatment-resistant conditions). The FDA has granted a <span class=\"s2\">Humanitarian Device Exemption (HDE)<\/span> for a DBS system for <span class=\"s2\">refractory obsessive-compulsive disorder<\/span> in adults (a narrow, specialized indication).<span class=\"Apple-converted-space\">\u00a0 <\/span><\/p>\n<h3><b>Vagus nerve stimulation (VNS)<\/b><\/h3>\n<p class=\"p3\"><span class=\"s2\"><b>VNS<\/b><\/span> uses an implanted device to send stimulation through the vagus nerve. The treatment involves sending regular, mild pulses of electrical energy to the brain via the vagus nerve, a large nerve in the neck. This is achieved through a device that is surgically implanted under the skin in the chest, similar to a pacemaker. A wire (lead) connected to this device is wound around the vagus nerve in the neck. The electrical pulses are delivered to the nerve by the device periodically throughout the day. It has long been used for epilepsy and has also received FDA approval for <span class=\"s2\"><b>treatment-resistant depression<\/b><\/span> under specific conditions and monitoring requirements.<span class=\"Apple-converted-space\">\u00a0 <\/span><\/p>\n<h3><b>Ketamine-assisted therapy and intranasal esketamine<\/b><\/h3>\n<p><b>Ketamine-assisted therapy <\/b>is<b><\/b> rapid-acting treatment for people with treatment-resistant depression (and other conditions like PTSD, chronic pain, or substance-abused disorders). Low-dose ketamine, a type of anesthetic (often given as six IV infusions over 2\u20134 weeks, or as intranasal esketamine) works by boosting glutamate-driven synapse growth. Relief can appear within hours and is paired with follow-up therapy sessions to reinforce lasting change. Clinics screen for cardiovascular and psychosis risk, monitor patients for about two hours post-dose, and reserve ketamine for those who haven\u2019t improved on standard medications.<\/p>\n<section class=\"textbox connectIt\">A buzzword in therapy today is<strong> evidence-based practice<\/strong>. However, it\u2019s not a novel concept but one that has been used in medicine for at least two decades. Evidence-based practice is used to reduce errors in treatment selection by making clinical decisions based on research (Sackett &amp; Rosenberg, 1995). In any case, evidence-based treatment is on the rise in the field of psychology. So what is it, and why does it matter?<\/p>\n<p>In an effort to determine which treatment methodologies are evidenced-based, professional organizations such as the American Psychological Association (APA) have recommended that specific psychological treatments be used to treat certain psychological disorders (Chambless &amp; Ollendick, 2001). According to the APA (2005), \u201cEvidence-based practice in psychology (EBPP) is the integration of the best available research with clinical expertise in the context of patient characteristics, culture, and preferences\u201d (p. 1).<\/p>\n<p>The foundational idea behind evidence-based treatment is that best practices are determined by research evidence that has been compiled by comparing various forms of treatment (Charman &amp; Barkham, 2005). These treatments are then operationalized and placed in treatment manuals\u2014trained therapists follow these manuals. The benefits are that evidence-based treatment can reduce variability between therapists to ensure that a specific approach is delivered with integrity (Charman &amp; Barkham, 2005). Therefore, clients have a higher chance of receiving therapeutic interventions that are effective at treating their specific disorder. While EBPP is based on randomized control trials, critics of EBPP reject it stating that the results of trials cannot be applied to individuals and instead determinations regarding treatment should be based on a therapist\u2019s judgment (Mullen &amp; Streiner, 2004).<\/p>\n<\/section>\n<section class=\"textbox tryIt\">\n<div class=\"group w-full text-token-text-primary border-b border-black\/10 gizmo:border-0 dark:border-gray-900\/50 gizmo:dark:border-0 gizmo:bg-transparent dark:bg-gray-800 gizmo:dark:bg-transparent\" data-testid=\"conversation-turn-66\">\n<div class=\"p-4 justify-center text-base md:gap-6 md:py-6 m-auto\">\n<div class=\"flex flex-1 gap-4 text-base mx-auto md:gap-6 gizmo:gap-3 gizmo:md:px-5 gizmo:lg:px-1 gizmo:xl:px-5 md:max-w-2xl lg:max-w-[38rem] gizmo:md:max-w-3xl gizmo:lg:max-w-[40rem] gizmo:xl:max-w-[48rem] xl:max-w-3xl }\">\n<div class=\"relative flex w-[calc(100%-50px)] flex-col gap-1 gizmo:w-full md:gap-3 lg:w-[calc(100%-115px)] gizmo:text-gizmo-gray-600 gizmo:dark:text-gray-300\">\n<div class=\"flex flex-grow flex-col gap-3 max-w-full\">\n<div class=\"min-h-[20px] flex flex-col items-start gap-3 overflow-x-auto whitespace-pre-wrap break-words\">\n<div class=\"\">What are some of the advantages and limitations of using biomedical therapies like psychotropic medications and electroconvulsive therapy (ECT) in the treatment of psychological disorders?<\/div>\n<\/div>\n<\/div>\n<div class=\"text-gray-400 flex self-end lg:self-center justify-center gizmo:lg:justify-start mt-2 gizmo:mt-0 invisible lg:gap-1 lg:absolute lg:top-0 lg:translate-x-full lg:right-0 lg:mt-0 lg:pl-2 gap-2 md:gap-3 gizmo:absolute gizmo:right-0 gizmo:top-1\/2 gizmo:-translate-y-1\/2 gizmo:transform\"><\/p>\n<div class=\"qa-wrapper\" style=\"display: block\"><button class=\"show-answer show-answer-button collapsed\" data-target=\"q636269\">Show Answer<\/button><\/p>\n<div id=\"q636269\" class=\"hidden-answer\" style=\"display: none\">\n<h3>Advantages of Biomedical Therapies<\/h3>\n<ol>\n<li>\n<p><strong>Immediate Relief<\/strong>: Psychotropic medications often provide quick relief from acute symptoms, making it easier for patients to participate in psychotherapy.<\/p>\n<\/li>\n<li>\n<p><strong>Accessibility<\/strong>: Medications are widely available and can be administered by general physicians, making treatment more accessible for many people.<\/p>\n<\/li>\n<li>\n<p><strong>Scientifically Backed<\/strong>: Treatments like ECT have shown high efficacy rates in treating severe depression and are often considered when other treatments fail.<\/p>\n<\/li>\n<li>\n<p><strong>Broad Application<\/strong>: Biomedical therapies can treat a wide range of psychological disorders, from depression and anxiety to schizophrenia and bipolar disorder.<\/p>\n<\/li>\n<\/ol>\n<h3>Limitations of Biomedical Therapies<\/h3>\n<ol>\n<li>\n<p><strong>Side Effects<\/strong>: Psychotropic medications often come with a range of side effects, from mild (e.g., drowsiness, nausea) to severe (e.g., tardive dyskinesia, increased risk of suicide).<\/p>\n<\/li>\n<li>\n<p><strong>Symptom Treatment, Not Cure<\/strong>: These therapies generally treat the symptoms but do not cure the underlying psychological disorder.<\/p>\n<\/li>\n<li>\n<p><strong>Over-reliance<\/strong>: There&#8217;s a risk of becoming overly reliant on medication, which can sometimes deter patients from pursuing other forms of treatment like psychotherapy.<\/p>\n<\/li>\n<li>\n<p><strong>Stigma<\/strong>: Both medication and especially ECT carry a societal stigma, which can affect a patient&#8217;s willingness to seek treatment.<\/p>\n<\/li>\n<li>\n<p><strong>Cost<\/strong>: Some of these treatments, particularly newer medications and procedures like deep brain stimulation, can be expensive and may not be covered by insurance.<\/p>\n<\/li>\n<li>\n<p><strong>Ethical Concerns<\/strong>: In the case of ECT, there are ethical considerations given its invasive nature and the potential for memory loss.<\/p>\n<\/li>\n<\/ol>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<p>&nbsp;<\/p>\n","protected":false},"author":20,"menu_order":16,"template":"","meta":{"_candela_citation":"[{\"type\":\"cc\",\"description\":\"Types of Treatment\",\"author\":\"OpenStax College\",\"organization\":\"\",\"url\":\"https:\/\/openstax.org\/books\/psychology-2e\/pages\/16-2-types-of-treatment\",\"project\":\"\",\"license\":\"cc-by\",\"license_terms\":\"Download for free at https:\/\/openstax.org\/books\/psychology-2e\/pages\/1-introduction\"},{\"type\":\"copyrighted_video\",\"description\":\"Biomedical Treatments: Crash Course Psychology #36\",\"author\":\"Hank Green\",\"organization\":\"CrashCourse\",\"url\":\"https:\/\/www.youtube.com\/watch?v=w2efaHgJ93A&feature=youtu.be&list=PL8dPuuaLjXtOPRKzVLY0jJY-uHOH9KVU6\",\"project\":\"\",\"license\":\"other\",\"license_terms\":\"Standard YouTube License\"},{\"type\":\"original\",\"description\":\"Modification, adaptation, and 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