Reconsolidation Therapy: Learn It 4—Memory Consolidation as a Treatment Method

This video shows the experimenters you have been reading about (Daniella Schiller and Elizabeth Phelps) discussing their work and you will even see a reenactment of part of the study. The video does not include many of the technical details you just went through, but it shows some of the procedures and the researchers give you some idea of the implications of their work.

You can view the transcript for “Erasing fear memories” here (opens in new window).

What is the practical value of this research?

At the very end of the video, you heard Dr. Phelps (from an interview in 2009) explain the potential for turning this research into a useful procedure for therapists:

So, you know, at this point, how this works in the clinic is going to be all speculation. But what this data suggests might happen in the future is: if you come into the clinic with a fear-related disorder, like a phobia or PTSD, if we can understand how these memories are re-stored when they are retrieved, much as we did in this study, we then may be able to time our therapeutic interventions in such a way where we aren’t creating new learning that’s overriding those earlier memories but actually rewriting them, in a sense. If we can time that correctly so we can target these mechanisms, perhaps we’d have a more effective, long-lasting outcome.

One of the goals of this research, then, is to give therapists a way of working with memory disorders. Of course, rather than creating a fear as the researchers did, therapists work with people who experience debilitating fear-related memories that came from experiences, often traumatic ones, in their lives. The therapist’s job is to help the person overcome the disabling experiences of fear. In most cases, they would like to reduce the emotional impact of the experience, which is part of the memory itself, without actually changing the facts that are remembered.

reconsolidation therapy

This application of reconsolidation theory to therapy is already underway. Here are the basic steps in this therapy:

  • REINSTATEMENT: Have the person retrieve the memory. Be sure that the retrieval is emotionally powerful. If the person avoids fully reactivating the memory in its complete painful form, then reduction of the emotional impact will be impossible. The emotion may be fear or anxiety or some other strong negative response.
  • REDUCTION OF EMOTIONAL IMPACT: While the memory is active and painful, the therapist acts to reduce its impact. There are two approaches to this. Let’s use the example of a phobia (irrational fear) to illustrate the methods:
    • EXTINCTION OF THE FEAR RESPONSE: In a therapy session, a person with a phobia (e.g., fear of spiders or dogs or heights) might (a) have the fear response reactivated (have them stand near a spider or dog or on a high perch) and then, (b) through continuous or repeated exposure to the source of fear with support from the therapist and experience of no bad consequences (not getting bitten or not falling), show a reduction of the fear response.
    • DRUGS THAT BLOCK FEAR MEMORY: In a therapy session, a person with a phobia (e.g., fear of spiders or dogs or heights) might (a) have the fear response reactivated (have them stand near a spider or dog or on a high perch) and then, (b) the person is given propranolol, a drug that inhibits the storage of emotional aspects of a memory.
  • REPETITION ACROSS DAY OR WEEKS: For a deep-seated problem, it is very unlikely that a single session will eliminate or even substantially reduce the automatic negative emotional response. The process of reinstatement followed by either extinction or drug intervention is necessary for effective treatment.